Bovine lactoferricin selectively induces apoptosis in human leukemia and carcinoma cell lines
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چکیده
منابع مشابه
Bovine lactoferricin selectively induces apoptosis in human leukemia and carcinoma cell lines.
Bovine lactoferricin (LfcinB) is a cationic, amphipathic peptide that is cytotoxic for human and rodent cancer cells. However, the mechanism by which LfcinB causes the death of cancer cells is not well understood. Here, we show that in vitro treatment with LfcinB rapidly induced apoptosis in several different human leukemia and carcinoma cell lines as determined by DNA fragmentation assays and ...
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متن کاملumbelliprenin induces apoptosis in cll cell lines
chronic lymphocytic leukemia (cll) remains an incurable disease that requires innovative new approaches to improve therapeutic outcome. many ferula species, including f. asa-foetida, synthesize terpenyloxy coumarins. one of these coumarins is umbelliprenin, which has been implicated with induction of apoptosis in some cancer cell lines. in this study induction of apoptosis by umbelliprenin ...
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ژورنال
عنوان ژورنال: Molecular Cancer Therapeutics
سال: 2005
ISSN: 1535-7163,1538-8514
DOI: 10.1158/1535-7163.mct-04-0077